Useful list compiled here at Linux Planet: The Top 75 Open Source Security Apps. Excerpt:

Anti-Virus/Anti-Malware

1. ClamWin Free Antivirus

This Windows-only app uses the incredibly popular ClamAV engine to detect viruses and spyware. It includes a scanning scheduler, automatic downloads, and a Microsoft Outlook plug-in. However, it does not provide real-time scanning; you'll need to scan your files manually in order to be protected. Operating System: Windows.

2. ClamAV

Numerous commercial and open-source products are based on the Clam Antivirus engine. Designed for protecting e-mail gateways, Clam AV offers automatic updates, a command line scanner, and more. Operating System: Unix, Linux, BSD.
...
Data Removal

14. Eraser

Want to make sure that file you deleted can never be retrieved? Eraser writes over your files with random data so that no one can snoop into your private files. Operating System: Windows and DOS.

15. Darik's Boot and Nuke

Also known as "DBAN," Darik's Boot and Nuke completely eliminates all of the data on a hard drive. It's an ideal way to clean up an old computer before you donate or recycle it. Operating System: OS Independent.

16. Wipe

Wipe erases all traces of deleted files from your hard drive so that they can't be retrieved. It relies heavily on the work of Peter Gutmann, one of the foremost experts in the field. Operating System: Linux.
...
Internet Security Suites

42. Winpooch

Calling itself "an opensource watchdog for Windows," Winpooch incorporates anti-spyware and anti-trojan capabilities with ClamWin Antivirus. It aims to give the user complete control over which programs are running on the system. Operating System: Windows.

43. DemocraKey

The DemocraKey tagline says it all: "It's like a condom for your computer." Install it on a portable drive and plug it in to any computer. DemocraKey scans for viruses and protects your privacy while you surf. Operating System: Windows.

There's a lot more to look at, if you're so inclined.

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